Theophylline action on sperm motility










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The data contradict previous reports and suggest that methyl xanthines do not have beneficial effects on the majority of semen samples obtained from men seen at a fertility evaluation clinic. Poor sperm motility is an important factor in male infertility. It appears that theophylline may be useful in improving the fertilizing capacity of selected human semen samples with poor motility and poor penetration ability under artificial insemination conditions. A similar twofold increase in egg penetration was observed in the semen of fertile men incubated with theophylline of similar concentrations.

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Sperm Motility Activation In The Critically

Concentrations of 10 -2 , 10 -3 , 10 -4 , 10 -5 , or 10 -6 M caffeine and theophylline were added to semen samples to determine the effects of these compounds on several parameters of semen quality. The data contradict previous reports and suggest that methyl xanthines do not have beneficial effects on the majority of semen samples obtained from men seen at a fertility evaluation clinic. There was a problem providing the content you requested Please contact us via our support center for more information and provide the reference number below. Poor sperm motility is an important factor in male infertility.

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The effects of caffeine and theophylline on the triple adenosine

Poor sperm motility is an important factor in male infertility. Neither of the compounds, at any of the dose levels tested, had any significantly different effects on the quality of sperm motility or the percentage of active or viable spermatozoa, although a few samples responded favorably to these compounds. Semen samples were incubated at 37 degrees C and observed 0. A similar twofold increase in egg penetration was observed in the semen of fertile men incubated with theophylline of similar concentrations. No significant difference in penetration rate was seen between 10 and 20 mM theophylline concentrations. It appears that theophylline may be useful in improving the fertilizing capacity of selected human semen samples with poor motility and poor penetration ability under artificial insemination conditions. The data contradict previous reports and suggest that methyl xanthines do not have beneficial effects on the majority of semen samples obtained from men seen at a fertility evaluation clinic.

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Description: It appears that theophylline may be useful in improving the fertilizing capacity of selected human semen samples with poor motility and poor penetration ability under artificial insemination conditions. Noted improvements in semen quality did not appear to be dependent on the initial semen quality. There was a problem providing the content you requested Please contact us via our support center for more information and provide the reference number below. No significant difference in penetration rate was seen between 10 and 20 mM theophylline concentrations. Semen quality was determined by estimating the percentage of active spermatozoa, by estimating sperm motility, and by counting the number of viable sperm at each time interval. Semen samples were incubated at 37 degrees C and observed 0.
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